LONDON (AP) -- Britain entered uncharted waters Friday after the country voted to leave the European Union, according to a projection by all main U.K. broadcasters. The decision shatters the stability of the project in continental unity forged after World War II in hopes of making future conflicts impossible.
The decision raises the likelihood of years of negotiations over trade, business and political links with what will become a 27-nation bloc. In essence the vote marks the start -- rather than the end -- of a process that could take decades to unwind.
The "leave" side was ahead by 51.7 percent to 48.3 percent with more than three-quarters of votes tallied, making a "remain" win a statistical near-impossibility.
The pound suffered one of its biggest one-day falls in history, plummeting more than 10 percent in six hours, from about $1.50 to below $1.35, on concern that severing ties with the single market will hurt the U.K. economy and undermine London's position as a global financial center.
But if it shocked the markets, the result delighted "leave" campaigners.
"The dawn is breaking on an independent United Kingdom," U.K. Independence Party leader Nigel Farage declared to loud cheers at a "leave" campaign party.
"Let June 23 go down in our history as our independence day!"
As results poured in, a picture emerged of a sharply divided nation: Strong pro-EU votes in the economic and cultural powerhouse of London and semi-autonomous Scotland were countered by sweeping anti-Establishment sentiment for an exit across the rest of England, from southern seaside towns to rust-belt former industrial powerhouses in the north.
"A lot of people's grievances are coming out and we have got to start listening to them," said deputy Labour Party leader John McDonnell.
With the result in favor of an EU exit, or Brexit, the U.K. becomes the first major country to decide to leave the bloc, which evolved in the ashes of the war as European leaders sought to build links and avert future hostility. Authorities ranging from the International Monetary Fund to the U.S. Federal Reserve and Bank of England warned a British exit will reverberate through a world economy that is only slowly recovering from the global economic crisis.
"The appeal of the anti-Establishment populist argument that we need to take back control of our borders and immigration ... proved stronger than the economic risks that Brexit would entail," said Tim Bale, a professor of politics at Queen Mary, University of London. "I think people are soon going to find out that the promise of the 'leave' campaign cannot possibly be realized."
The vote is likely to cost Prime Minister David Cameron his job after the leader of the ruling Conservative Party staked his reputation on keeping Britain in the EU. Former London Mayor Boris Johnson was the most prominent supporter of the "leave" campaign and is now seen as a leading contender to replace Cameron.
Cameron promised the referendum to appease the right wing of his own party and blunt a challenge from the U.K. Independence Party, which pledged to leave the EU. After winning a majority in Parliament in the last election, Cameron negotiated a package of reforms that he said would protect Britain's sovereignty and prevent EU migrants from moving to the U.K. to claim generous public benefits.
Critics charged that the reforms were hollow, leaving Britain at the mercy of bureaucrats in Brussels and doing nothing to stem the tide of European immigrants who have come to the U.K. since the EU expanded eastward in 2004. The "leave" campaign accuses the immigrants of taxing Britain's housing market, public services and employment.
Those concerns were magnified by the refugee crisis of the past year that saw more than 1 million people from the Middle East and Africa flood into the EU as the continent's leaders struggled to come up with a unified response.
Cameron's efforts to find a slogan to counter the "leave" campaign's emotive "take back control," settled on "Brits don't quit." But the appeal to a Churchillian bulldog spirit and stoicism proved too little, too late.
The slaying of pro-Europe lawmaker Jo Cox a week before the vote brought a shocked pause to both campaigns and appeared to shift momentum away from the "leave" camp. While it isn't clear whether her killer was influenced by the EU debate, her death aroused fears that the referendum had stirred demons it would be difficult to subdue.
The result triggers a new series of negotiations that is expected to last two years or more as Britain and the EU search for a way to separate economies that have become intertwined since the U.K. joined the bloc on Jan. 1, 1973. Until those talks are completed, Britain will remain a member of the EU.
Exiting the EU involves taking the unprecedented step of invoking Article 50 of the EU's governing treaty. While Greenland left an earlier, more limited version of the bloc in 1985, no country has ever invoked Article 50, so there is no roadmap for how the process will work.
"It will usher in a lengthy and possibly protracted period of acute economic uncertainty about the U.K.'s trading arrangements," said Daniel Vernazza, the U.K. economist at UniCredit.
The European Union is the world's biggest economy and the U.K.'s most important trading partner, accounting for 45 percent of exports and 53 percent of imports.
In addition, the complex nature of Britain's integration with the EU means that breaking up will be hard to do. The negotiations will go far beyond tariffs, including issues such as cross-border security, foreign policy cooperation and a common fisheries policy.
Among the biggest challenges for Britain is protecting the ability of professionals such as investment managers, accountants and lawyers to work in the EU.
As long as the U.K. is a member of the bloc, firms registered in Britain can operate in any other member state without facing another layer of regulation. It's the same principle that allows exporters to ship their goods to any EU country free of tariffs.
Now that right is up for negotiation, threatening the City, as London's financial heart is known, and its position as Europe's pre-eminent financial center.
Many international banks and brokerages have long used Britain as the entry point to the EU because of its trusted legal system and institutions that operate in English, the language of international finance. Britain's financial services industry is also surrounded by an ecosystem of expertise -- lawyers, accountants and consultants-- that support it.
Some 60 percent of all non-EU firms have their European headquarters in the U.K., according to TheCityUK, which lobbies on behalf of the financial industry. The U.K. hosts more headquarters of non-EU firms than Germany, France, Switzerland and the Netherlands put together.
"We believe this outcome has serious implications for the City and many of our clients' businesses with exposure to the U.K. and the EU," said Malcolm Sweeting, senior partner of the law firm, Clifford Chance. "We are working alongside our clients to help them as they anticipate, plan for and manage the challenges the coming political and trade negotiations will bring."
JPMorgan Chase Chief Executive Jamie Dimon said earlier this month that a vote to leave would force his bank to move jobs to mainland Europe to ensure that it could continue to service clients in the EU. Other global businesses with customers in the rest of the EU will be in a similar situation.
The only question that remains is whether the dire economic predictions economists made during the campaign will come to pass.
"Uncertainty is bad for business," Vernazza said. "A sharp fall in U.K. risky asset prices, delays to investment, disruption to trade, and a loss of business and consumer confidence mean the U.K. economy is more likely than not to enter a technical recession within two years."
Associated Press writers Raphael Satter in London and Shawn Pogatchnik in Dublin contributed to this report.