MILAN (AP) -- Roma's miserable month continued as it crashed out of the Italian Cup on Wednesday, losing 4-2 on penalties to second-division Spezia.
Miralem Pjanic and Edin Dzeko missed Roma's first two spot kicks after the match had finished goalless after extra time.
Spezia scored all four of theirs to book a quarterfinal tie against third-division Alessandria, which has knocked out Palermo and Genoa.
Roma, which is through to the knockout stages of the Champions League, has not won in any competition since beating Lazio in the capital derby on Nov. 8.
Relegation-threatened Carpi also pulled off an upset, with Antonio Di Gaudio scoring the only goal in a 1-0 victory at Fiorentina.
Holder Juventus hosts Torino in a derby later, while Napoli welcomes Hellas Verona.