DENVER (AP) -- In only the fourth-ever NFL meeting of teams unbeaten after six games or more, Denver beat Green Bay 29-10 on Sunday and quarterback Peyton Manning tied Brett Favre's league record with his 186th regular-season win.
Manning and the Broncos took a victory that showcased their title credentials, while Packers quarterback Aaron Rodgers had one of the worst games of his career.
In other key results, New Orleans beat the New York Giants 52-49 in a game with an NFL record 13 touchdown passes and an extraordinary climax; Cincinnati downed Pittsburgh to make seven straight wins to start a season for the first time in Bengals history, and Seattle defeated Dallas by a point to get back square with a 4-4 record.
Denver, wearing the blue jerseys they did in beating the Packers for their first Super Bowl win in 1997, improved to 7-0 for the first time since 1998, when they won the Super Bowl after finishing 14-2.
Rodgers completed 14 of 22 passes for just 77 yards for the Packers (6-1) -- the lowest yardage of his career in a game where he wasn't knocked out by injury.
Although neither quarterback threw for a touchdown, Manning was 21 of 29 for 340 yards. The Packers had only 140 yards of total offense to Denver's 500.
New Orleans quarterback Drew Brees passed for career highs of 511 yards and seven touchdowns, and recently signed Kai Forbath kicked a 50-yard field goal as time ran out to give the Saints a memorable 52-49 win against the Giants.
New York quarterback Eli Manning came out on the losing end despite a career-high six touchdown passes, three to fellow New Orleans native Odell Beckham Jr.
The 101 points tied for third most in NFL history. The teams combined for 1,030 yards.
The score was tied and the Giants punted with 20 seconds to go. The punt stayed in play, and Marcus Murphy returned it across the 50 and fumbled, but the Saints recovered the ball and the Giants were flagged for a face mask penalty which put the winning kick within achievable distance and Forbath slotted it.
The return of Pittsburgh quarterback Ben Roethlisberger from a month out injured was not enough for the Steelers, who gave up the lead late and lost 16-10 to Cincinnati.
Bengals quarterback Andy Dalton threw a touchdown pass with 2:57 to go, and the Bengals picked off Roethlisberger twice in the fourth quarter.
After the Bengals took the lead, Roethlisberger and the Steelers had one more scoring chance with four seconds left but his pass went out of the end zone to finish it.
Seattle's Russell Wilson had a scoring pass for the game's only touchdown and directed a late drive to the winning field goal, leading the defending NFC champions to a 13-12 win against Dallas.
The Cowboys (2-5) lost their fifth straight without quarterback Tony Romo and despite Dez Bryant's return from a five-game absence with a broken right foot.
The Seahawks started the decisive drive at their 15, with Wilson converting three third downs capped by a scramble that helped run the clock before Steven Hauschka's 24-yard field goal with 1:06 remaining.
Tampa Bay recovered from blowing a 17-point lead and got a 31-yard field goal from Connor Barth in overtime to beat mistake-prone Atlanta 23-20.
Falcons quarterback Matt Ryan tied the game with an 8-yard pass to Julio Jones with 17 seconds left in regulation. Having squandered a 24-point lead the previous week at Washington, the Buccaneers were in trouble again.
Instead, Jameis Winston led an impressive drive on the first possession of OT, converting three times on third down before Barth kicked his third field goal of the game to win it.
Arizona's Carson Palmer threw for four touchdowns, three in the second half, and for 374 yards as the Cardinals beat Cleveland 34-20.
Palmer had two TD passes in the third quarter when the Cardinals overcame a 20-10 halftime deficit. His third TD of the second half, a 6-yarder to Larry Fitzgerald, gave Arizona a 31-20 lead.
The Cardinals overcame four turnovers and won in Cleveland for the first time since 1985.
Minnesota's Adrian Peterson ran for 103 yards and Blair Walsh kicked a 36-yard field goal as time expired to give the Vikings a 23-20 victory over Chicago.
Baltimore's Justin Tucker kicked a 39-yard field goal on the final play and Joe Flacco threw for 319 yards and ran for a score to help the Ravens beat San Diego 29-26 and hand the Chargers their fourth straight defeat.
St. Louis' Todd Gurley rushed for 133 yards on 20 carries, topping 100 yards for the fourth straight start to open his career, and the Rams had three sacks and a safety in beating San Francisco 27-6.
Oakland's Derek Carr threw for 333 yards and four touchdowns to help the Raiders pick apart the New York Jets' vaunted defense and win 34-20.
Houston tied a franchise record with seven sacks and beat Tennessee 20-6, with Brian Hoyer throwing for 235 yards and two touchdowns.
Kansas City's Alex Smith threw for 145 yards and two touchdowns and ran for 78 yards and another TD to lead the Chiefgs over Detroit 45-10 at Wembley Stadium in London.
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