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The interior of a home is filled with floodwater brought by Tropical Storm Isaac in Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Is... The interior of a home is filled with floodwater brought by Tropical Storm Isaac in Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/Dieu Nalio Chery)
APTOPIX Haiti Tropical Weather
A man stands next to his bed after Tropical Storm Isaac destroyed his home and others at a camp set up for people displaced by the 2010 earthquake in... A man stands next to his bed after Tropical Storm Isaac destroyed his home and others at a camp set up for people displaced by the 2010 earthquake in Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/Dieu Nalio Chery)
Haiti Tropical Weather
A man carries a child as residents leave an area flooded by Tropical Storm Isaac in Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Is... A man carries a child as residents leave an area flooded by Tropical Storm Isaac in Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/Dieu Nalio Chery)
Haiti Tropical Weather
In this photo released by the U.N. mission in Haiti, MINUSTAH, a woman swims through flood waters in a low lying area affected by Tropical Storm Isaa... In this photo released by the U.N. mission in Haiti, MINUSTAH, a woman swims through flood waters in a low lying area affected by Tropical Storm Isaac in Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/MINUSTAH, Logan Abassi)
APTOPIX Haiti Tropical Weather
A boy tries to take cover from the cold behind an appliance sitting higher than the floodwaters triggered by Tropical Storm Isaac in Port-au-Prince, ... A boy tries to take cover from the cold behind an appliance sitting higher than the floodwaters triggered by Tropical Storm Isaac in Port-au-Prince, Haiti, Saturday Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/Dieu Nalio Chery)
Haiti Tropical Weather
In this photo released by the U.N. mission in Haiti, MINUSTAH, residents leave their flooded homes in a low lying area affected by Tropical Storm Isa... In this photo released by the U.N. mission in Haiti, MINUSTAH, residents leave their flooded homes in a low lying area affected by Tropical Storm Isaac in Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/MINUSTAH, Logan Abassi)
APTOPIX Haiti Tropical Weather
A man carrying a bottle in his mouth slips as he wades through a flooded street, triggered by Tropical Storm Isaac, in Port-au-Prince, Haiti, Saturda... A man carrying a bottle in his mouth slips as he wades through a flooded street, triggered by Tropical Storm Isaac, in Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/Dieu Nalio Chery)
Haiti Tropical Weather
A voodoo cross in honor of the Baron Samedi stands in floodwaters, triggered by Tropical Storm Isaac, at a place of worship in Port-au-Prince, Haiti,... A voodoo cross in honor of the Baron Samedi stands in floodwaters, triggered by Tropical Storm Isaac, at a place of worship in Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/Dieu Nalio Chery)
APTOPIX Cuba Tropical Weather
A man stands on a post with a stop sign as waves pass the seawall during the passage of Tropical Storm Isaac in Baracoa, Cuba, Saturday, Aug. 25, 201... A man stands on a post with a stop sign as waves pass the seawall during the passage of Tropical Storm Isaac in Baracoa, Cuba, Saturday, Aug. 25, 2012. Tropical Storm Isaac pushed into Cuba on Saturday after sweeping across Haiti's southern peninsula. Isaac's center made landfall just before midday near the far-eastern tip of Cuba. (AP Photo/Ramon Espinosa)
APTOPIX Cuba Tropical Weather
A home that was built twice within the last two years is left in ruins during the passage of Tropical Storm Isaac near the seawall in Baracoa, Cuba, ... A home that was built twice within the last two years is left in ruins during the passage of Tropical Storm Isaac near the seawall in Baracoa, Cuba, Saturday, Aug. 25, 2012. Tropical Storm Isaac pushed into Cuba on Saturday after sweeping across Haiti's southern peninsula. Isaac's center made landfall just before midday near the far-eastern tip of Cuba. (AP Photo/Ramon Espinosa)
Cuba Tropical Weather
Men stand behind the seawall as waves brought by Tropical Storm Isaac splash over them in Baracoa, Cuba, Saturday, Aug. 25, 2012. Tropical Storm Isaa... Men stand behind the seawall as waves brought by Tropical Storm Isaac splash over them in Baracoa, Cuba, Saturday, Aug. 25, 2012. Tropical Storm Isaac pushed into Cuba on Saturday after sweeping across Haiti's southern peninsula. Isaac's center made landfall just before midday near the far-eastern tip of Cuba. (AP Photo/Ramon Espinosa)
Tropical Weather
The southernmost point marker is covered in plastic sheeting in Key West, Fla., Saturday, Aug. 25, 2012, in preparation for Tropical Storm Isaac, Sat... The southernmost point marker is covered in plastic sheeting in Key West, Fla., Saturday, Aug. 25, 2012, in preparation for Tropical Storm Isaac, Saturday, Aug. 25, 2012. Isaac's winds are expected to be felt in the Florida Keys by sunrise Sunday morning. (AP Photo/Alan Diaz)
Tropical Weather
Cheri Senecal walks with a bag of personal items to a shelter in Key West, Fla., Saturday, Aug. 25, 2012 as she prepares for Tropical Storm Isaac, Sa... Cheri Senecal walks with a bag of personal items to a shelter in Key West, Fla., Saturday, Aug. 25, 2012 as she prepares for Tropical Storm Isaac, Saturday, Aug. 25, 2012. Isaac's winds are expected to be felt in the Florida Keys by sunrise Sunday morning. (AP Photo/Alan Diaz)
Tropical Weather
Richie Moretti, left, and Bette Zirkelback release a kemps ridley turtle into an indoor tank in Marathon, Fla., Saturday, Aug. 25, 2012 . The turtles... Richie Moretti, left, and Bette Zirkelback release a kemps ridley turtle into an indoor tank in Marathon, Fla., Saturday, Aug. 25, 2012 . The turtles were moved from outside tanks to safer indoor tanks for protection in anticipation of Tropical Storm Isaac, Saturday, Aug. 25, 2012. Isaac's winds are expected to be felt in the Florida Keys by sunrise Sunday morning. (Alan Diaz)
Tropical Weather
Yoni Haim, left, and Jessica Yeshalek board their storefront as they prepare for Tropical Storm Isaac, Saturday, Aug. 25, 2012. Isaac's winds are exp... Yoni Haim, left, and Jessica Yeshalek board their storefront as they prepare for Tropical Storm Isaac, Saturday, Aug. 25, 2012. Isaac's winds are expected to be felt in the Florida Keys by sunrise Sunday morning. (AP Photo/Alan Diaz)
Tropical Weather
Oren Eshel boards a storefront on Duval Street in Key West, Fla., Saturday, Aug. 25, 2012 in preparation for Tropical Storm Isaac, Saturday, Aug. 25,... Oren Eshel boards a storefront on Duval Street in Key West, Fla., Saturday, Aug. 25, 2012 in preparation for Tropical Storm Isaac, Saturday, Aug. 25, 2012. Isaac's winds are expected to be felt in the Florida Keys by sunrise Sunday morning. (AP Photo/Alan Diaz)
Haiti Tropical Weather
A family salvages what is left of their home at a camp set up for people displaced by the 2010 earthquake that was destroyed by Tropical Storm Isaac ... A family salvages what is left of their home at a camp set up for people displaced by the 2010 earthquake that was destroyed by Tropical Storm Isaac in Port-au-Prince, Haiti, Saturday Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/Dieu Nalio Chery)
Haiti Tropical Weather
A man works to repair the roof of his tent in a camp for people displaced by the 2010 earthquake as Tropical Storm Isaac affects Port-au-Prince, Hait... A man works to repair the roof of his tent in a camp for people displaced by the 2010 earthquake as Tropical Storm Isaac affects Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/Dieu Nalio Chery)
Haiti Tropical Weather
A man works to repair the roof of his tent in a camp for people displaced by the 2010 earthquake as Tropical Storm Isaac affects Port-au-Prince, Hait... A man works to repair the roof of his tent in a camp for people displaced by the 2010 earthquake as Tropical Storm Isaac affects Port-au-Prince, Haiti, Saturday, Aug. 25, 2012. Tropical Storm Isaac swept across Haiti's southern peninsula early Saturday, dousing a capital city prone to flooding and adding to the misery of a poor nation still trying to recover from the 2010 earthquake. (AP Photo/Dieu Nalio Chery)
Forecasters say it's unlikely that Tropical Storm Isaac will strengthen into a hurricane before it hits the Florida Keys.
However, it is still expected to gain strength as it moves over the open waters of the Gulf of Mexico. It could make landfall somewhere along the northern Gulf Coast. It's not clear exactly where it will hit, but forecasters say hurricane conditions are possible anywhere from the New Orleans area to the Florida Panhandle.
Isaac already started pelting the Florida Keys with rain and strong winds on Sunday.
The U.S. National Hurricane Center in Miami says Isaac was about 50 miles (80 kilometers) south-southeast of Key West, Fla. Its top sustained winds had decreased to 60 mph (97 kph).