Liverpool begins its Europa League campaign at home to Rabotnicki of Macedonia or Armenian club Mika in the third qualifying round.
Italy's Juventus, the other traditional power in Friday's draw, is away to Ireland's Shamrock Rovers or Bnei Yehuda of Israel, who complete a second qualifying round tie next week.
Liverpool and Juventus are three-time winners of the UEFA Cup, the second-tier competition which was rebranded as the Europa League last year.
Both storied teams finished seventh in their domestic leagues last season, failing to qualify for the Champions League.
First-leg matches are played July 29 and returns on Aug. 5.
Winners advance to the playoff round before progressing to the group stage.