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Researchers find link between male hormone and liver cancer

Researchers find link between male hormone and liver cancer

A team of Taiwanese doctors have found a way to repress male hormones in what could lead to the prevention of liver cancer, reports said yesterday.
The team led by China Medical University Professor Chang Chawnshang used animal testing to prove for the first time that the androgen receptor can cause liver cancer, according to a report published in the United States by "Science Translational Medicine" magazine.
If the male hormone or androgen receptor could be suppressed, the number of incidences of hepatitis B and later liver cancer could be cut, Chang said.
Chang presented his research to the Cabinet-level National Science Council in a report yesterday about new medicine against liver cancer.
National Taiwan University hepatitis specialist Chen Ting-hsin had the experience of using the hepatitis B-virus vaccine to reduce the occurrence of hepatitis B in children as well as cases of liver cancer, reports said. Chen's experience proved that the two diseases were related, according to reports.
The role of the androgen receptor was extremely important, Chang said, because it causes hepatitis B in men to transform itself rather rapidly into liver cancer. His team's research was the first to use mice to show why men were more susceptible to fall prey to liver cancer than women, Chang said.
The team also extracted elements from ginger and curry it injected into mice to reduce the creation of cancer. The experience also showed there was a possibility that in the future doctors could develop a cure or a medicine that could prevent the emergence of liver cancer by repressing the androgen receptor.
"Science Translational Medicine" magazine held a news conference in Washington, D.C. on May 20 to announce the publication of the Chang team's research, reports said. The hepatitis story also featured on the magazine's cover.